TY  - JOUR
T1  - CHange in medium for scarlet fever toxin
AU  - Dick GH
Y1  - 1939/09/16
N1  - 10.1001/jama.1939.02800370066027
JO  - Journal of the American Medical Association
SP  - 1150
EP  - 1150
VL  - 113
IS  - 12
N2  - To the Editor:— 
    Some persons who have received injections of diphtheria toxoid, especially the alum precipitated toxoid, may be sensitized to proteins contained in veal broth and consequently develop urticaria following injection of other veal broth preparations.To avoid the development of urticaria in such persons during the course of immunization against scarlet fever, the medium in which scarlet fever toxin is produced has been changed to one which contains no meat infusion. Use of this medium results in a toxin containing considerably less protein and a marked reduction in the incidence of urticaria.
SN  - 0002-9955
M3  - doi: 10.1001/jama.1939.02800370066027
UR  - http://dx.doi.org/10.1001/jama.1939.02800370066027
ER  -