TY  - JOUR
T1  - TRansplantation of adrenal cortex for addison's disease
Y1  - 1939/09/09
N1  - 10.1001/jama.1939.02800360048015
JO  - Journal of the American Medical Association
SP  - 1034
EP  - 1035
VL  - 113
IS  - 11
N2  - The feasibility of successful transplantation of the adrenal gland in animals has been demonstrated by a number of investigators. The rat, according to Jaffe,1 offers excellent opportunities for such a study. In his experience successful transplants were obtained in at least 80 per cent of attempts. The process of regeneration was completed in from three to four weeks, after which time the transplant grew and reached the size of a normal gland. Jaffe and Plavska's autoplastic transplants in guinea pigs maintained their animals for months after the removal of the second main gland. These results appear to be conclusive of function when the results are compared with the results for guinea pigs whose adrenals were removed and in which transplants were not done; these survived three or four days. Elliott and Tuckett2 observed that the subcutaneous tissues of guinea pigs are peculiarly sensitive to adrenal grafts, which produce
SN  - 0002-9955
M3  - doi: 10.1001/jama.1939.02800360048015
UR  - http://dx.doi.org/10.1001/jama.1939.02800360048015
ER  -