TY  - JOUR
T1  - THe "vertical" transmission of cancer
Y1  - 1949/09/17
N1  - 10.1001/jama.1949.02910030032008
JO  - Journal of the American Medical Association
SP  - 202
EP  - 203
VL  - 141
IS  - 3
N2  - The suggestion that cancer is caused by viruses transmitted "vertically" from one generation to another is made by L. Gross1 of the Veterans Administration Hospital, New York. Mammary carcinoma of mice is caused by a filterable agent which is transmitted through the milk of nursing females.2 This agent is destroyed by heating to 61 C. for thirty minutes3 and can be neutralized by a specific immune serum.4 The development of mammary carcinoma in mice can be prevented by simply isolating newly born animals from their potentially cancerous mothers and transferring them for nursing to mice whose milk is free from the tumor agent. The newly born mice become infected by the milk of their mothers; they remain in perfect health, however, through early adult life, mammary carcinoma developing at 1 to 1 1/2 years of age. In the meantime, they may transfer the tumor agent to
SN  - 0002-9955
M3  - doi: 10.1001/jama.1949.02910030032008
UR  - http://dx.doi.org/10.1001/jama.1949.02910030032008
ER  -