TY  - JOUR
T1  - A method for the dark field examination of pus for spirochaeta pallida
AU  - Friedman L
Y1  - 1939/01/14
N1  - 10.1001/jama.1939.62800020001008a
JO  - Journal of the American Medical Association
SP  - 134
EP  - 135
VL  - 112
IS  - 2
N2  - The visible contamination of a specimen of serum with cellular elements and débris renders that specimen almost useless for direct dark field examination for Spirochaeta pallida. Various technics have been devised for the preparation of a suggestive lesion in order to obtain a satisfactory specimen for dark field examination,1 but no method has been previously developed to convert a pus or blood contaminated specimen into one suitable for adequate dark field study. Carley2 advocates the dark field examination of urethral discharge when there is any suspicion of syphilis but states that this is not possible in all cases. In fact, Dr. John H. Stokes3 in commenting on the detection of syphilis in a urologic clinic stated: "A gonorrheal discharge contains so many pus cells that dark field examination is as unsatisfactory as from a heavily blood contaminated specimen. The white blood cell does not undergo lysis as
SN  - 0002-9955
M3  - doi: 10.1001/jama.1939.62800020001008a
UR  - http://dx.doi.org/10.1001/jama.1939.62800020001008a
ER  -