TY  - JOUR
T1  - AN antianemic factor in desiccated stomach
AU  - SHARP EA
Y1  - 1929/09/07
N1  - 10.1001/jama.1929.02710100011005
JO  - Journal of the American Medical Association
SP  - 749
EP  - 749
VL  - 93
IS  - 10
N2  - Liver and liver extracts have proved to be specific in the treatment of pernicious anemia. The question of why they are effective cannot be answered. Tashiro1 believes that an impaired liver function actuates primary anemia. Meinertz2 regards the spleen as the cause of hemolysis with a coincident subnormal liver function in caring for the toxic products of amino-acid oxidation. Eleven years ago Mosenthal3 raised the point that protein destruction plays a considerable rôle in the etiology of pernicious anemia. Means and Richardson4 express the view that there is a shortage of a specific substance clearly responsible for the abnormalities in the bone marrow and the blood.Koessler5 and his co-workers have produced experimental anemia in animals with a blood picture similar to that of pernicious anemia by a diet deficient in vitamin A. They followed up this observation in human cases of the disease by
SN  - 0002-9955
M3  - doi: 10.1001/jama.1929.02710100011005
UR  - http://dx.doi.org/10.1001/jama.1929.02710100011005
ER  -