TY - JOUR T1 - DEsiccated stomach in the treatment of pernicious anemia AU - STURGIS CC, ISAACS R Y1 - 1929/09/07 N1 - 10.1001/jama.1929.02710100009004 JO - Journal of the American Medical Association SP - 747 EP - 749 VL - 93 IS - 10 N2 - After the discovery by Minot and Murphy1 of the beneficial effects of liver therapy in pernicious anemia and the preparation of an active extract by Cohn and his associates,2 the way for further study was opened by the demonstration by Castle3 that the stomach of normal persons secreted a substance which could develop a blood-maturing principle from meat. After a consideration of these investigations, it seemed advisable to us to test the activity of gastric tissue itself. Work was started at the Simpson Memorial Institute on the nature of the material in stomach which could produce a hematopoietically active substance, but the experiments were later carried on with the association of Dr. Elwood A. Sharp, director of the department of experimental medicine of Parke, Davis and Company. Dr. Sharp, working on the basis of an original theory, concluded that the feeding of stomach should have the same SN - 0002-9955 M3 - doi: 10.1001/jama.1929.02710100009004 UR - http://dx.doi.org/10.1001/jama.1929.02710100009004 ER -