TY - JOUR T1 - THe mechanism of fat absorption Y1 - 1929/07/06 N1 - 10.1001/jama.1929.02710010043013 JO - Journal of the American Medical Association SP - 37 EP - 37 VL - 93 IS - 1 N2 - Most writers who deal with the mode of absorption of fat from the alimentary tract are at present inclined to the view that it is disintegrated by lipolytic enzymes into fatty acids and glycerol before it penetrates the intestinal barrier.1 As the lymph stream that carries the products of absorption away from the intestine contains neutral fats, it is assumed that a resynthesis of the liberated fatty acids to fat occurs somewhere along the route between the lumen of the bowel and the lymphatic channels. One would expect the locus of such changes to be in the cells of the intestinal mucosa. Sinclair2 has pointed out that the resynthesis of fat is assumed tacitly to be simply a reversal of the hydrolysis which takes place in the lumen of the intestine; that is, it is enzymic in nature. Nevertheless, attempts to demonstrate in vitro the synthesis of fat SN - 0002-9955 M3 - doi: 10.1001/jama.1929.02710010043013 UR - http://dx.doi.org/10.1001/jama.1929.02710010043013 ER -