TY  - JOUR
T1  - THe metabolism of bile acids
Y1  - 1919/08/30
N1  - 10.1001/jama.1919.02610350042017
JO  - Journal of the American Medical Association
SP  - 694
EP  - 695
VL  - 73
IS  - 9
N2  - The daily discharge of a pint of secretion containing more than half an ounce (15 gm.) of substances, of which several are chemically unique, into the alimentary tract is a phenomenon that ought to excite considerable interest and speculation. Abnormalities of the biliary functions, to which we obviously refer here, are a frequent problem for surgical consideration as well as a source of pathologic manifestations that every physician is called on to treat. Nevertheless, the physiology of the bile still continues to be enshrouded in no little mystery. The importance of the bile in certain of the digestive functions, particularly in relation to the utilization of fats, has come to be well realized. It is sometimes claimed of late that this secretion acts as a regulator of intestinal putrefaction, because of a slight laxative property whereby the intestinal contents are expelled before bacteria develop in them to any great extent;
SN  - 0002-9955
M3  - doi: 10.1001/jama.1919.02610350042017
UR  - http://dx.doi.org/10.1001/jama.1919.02610350042017
ER  -