TY - JOUR T1 - THe course of events in secondary wound shock AU - CANNON WB Y1 - 1919/07/19 N1 - 10.1001/jama.1919.02610290016008 JO - Journal of the American Medical Association SP - 174 EP - 181 VL - 73 IS - 3 N2 - In the issues of The Journal of February 23 and March 2, 1918, there was published a series of articles by Cowell, Fraser, Hooper and myself which described certain clinical observations that we had made on soldiers who suffered from shock and allied conditions. These observations confirmed earlier reports on the persistent low arterial pressure, the rapid pulse and respiration, and the lowered body temperature of the shock state; they also revealed a concentration of corpuscles in the capillaries, a reduction of the alkali reserve corresponding in general to the degree of lowering of arterial pressure, a marked sensitiveness to ether or chloroform anesthesia, and a tolerance of nitrous oxid and oxygen as an anesthetic. On the basis of these facts a definition of traumatic or wound shock might be offered; it is a general bodily state occurring after severe injury and characterized by persistent low arterial pressure, rapid pulse, SN - 0002-9955 M3 - doi: 10.1001/jama.1919.02610290016008 UR - http://dx.doi.org/10.1001/jama.1919.02610290016008 ER -