TY  - JOUR
T1  - THe nature of autolysis
Y1  - 1919/01/11
N1  - 10.1001/jama.1919.02610020036013
JO  - Journal of the American Medical Association
SP  - 118
EP  - 119
VL  - 72
IS  - 2
N2  - The softening or liquefaction of dead tissues without the intervention of bacterial putrefactive processes has long been recognized as a biologic possibility. In 1890, Salkowski announced that this postmortem self-digestion, or "autodigestion," as he termed it, is due to enzymatic changes of the sort subsequently designated as intracellular. The expression "autolysis" now in vogue to designate the same phenomena was introduced in 1900 by Jacoby. Since then it has gained increasing prominence in relation to various problems of chemical pathology. The importance assigned to the subject is indicated by the fact that some investigators have even regarded postmortem autolysis as a continuation of a normal intravital process; hence it was believed that a thorough understanding of the mechanism of autolysis might give a clue to the phenomena of protein changes in the living cell. As one writer3 has expressed it, "It may be assumed with certainty that no one
SN  - 0002-9955
M3  - doi: 10.1001/jama.1919.02610020036013
UR  - http://dx.doi.org/10.1001/jama.1919.02610020036013
ER  -