TY - JOUR T1 - A 35-year-old physician with opioid dependence AU - Knight JR Y1 - 2004/09/15 N1 - 10.1001/jama.292.11.1351 JO - JAMA SP - 1351 EP - 1357 VL - 292 IS - 11 N2 - Some time later, Dr L became ill with an upper respiratory tract infection. Again, he self-treated his symptoms, this time with a cough syrup containing hydrocodone that he obtained from his office sample closet. The hydrocodone improved not only his cough but also his mood, and he began to take it regularly to get through the day, even after his cough resolved. It allowed him to function at a level he perceived as higher than his normal baseline: he was productive, attentive, happy, and energized. He began requiring more and more of the hydrocodone to achieve these effects. SN - 0098-7484 M3 - doi: 10.1001/jama.292.11.1351 UR - http://dx.doi.org/10.1001/jama.292.11.1351 ER -