TY - JOUR T1 - THe impact of the polymerase chain reaction in clinical medicine AU - Post J, Ehrlich GD Y1 - 2000/03/22 N1 - 10.1001/jama.283.12.1544 JO - JAMA SP - 1544 EP - 1546 VL - 283 IS - 12 N2 - Consider the plight of the medieval scholar. Before the advent of movable type, scholarship was greatly hindered by a lack of access to necessary texts. Even a journey to the library of a far-away monastery did not guarantee finding one of the few existing copies of a book, and the volume, once found after a long search, might prove to be a faulty copy produced by a careless scribe. Gutenberg's invention of printing from movable type revolutionized scholarship, leading to an explosion of new knowledge. Any number of copies of exactly replicated texts could be produced, greatly enhancing the probability that the scholar would come across the needed information, and in turn produce new information that could be shared with others. SN - 0098-7484 M3 - doi: 10.1001/jama.283.12.1544 UR - http://dx.doi.org/10.1001/jama.283.12.1544 ER -