TY - JOUR T1 - AN international study of patient compliance with hemodialysis AU - Bleyer AJ, Hylander B, Sudo H, et al Y1 - 1999/04/07 N1 - 10.1001/jama.281.13.1211 JO - JAMA SP - 1211 EP - 1213 VL - 281 IS - 13 N2 - Context  International differences in compliance of patients undergoing hemodialysis are poorly characterized and could contribute to international survival differences.Objective  To compare international differences in patient compliance with hemodialysis treatments.Design  A prospective observational study of patients undergoing hemodialysis in 1995 and a cross-sectional survey of health care professionals caring for hemodialyzed patients in 1996.Setting and Patients  Four dialysis centers in the southeastern United States with 415 patients undergoing hemodialysis, 1 center in Sweden with 84 patients, and 4 centers in Japan with 194 patients participated in the prospective observational study. In the cross-sectional survey, nurses and nephrologists from the United States (n=49), Japan (n=21), and Sweden (n=16) responded to questions regarding the compliance of their patients undergoing hemodialysis.Main Outcome Measures  Percentage of patients who miss a dialysis treatment and number of missed dialysis treatments.Results  Of 415 US patients, 147 missed 699 treatments over a 6-month period (28.1 missed treatments per 100 patient-months or 2.3% of all prescribed treatments). During a 3-month period, there were 0 missed treatments per 100 patient-months for patients from Japan and 0 missed treatments per 100 patient-months for patients from Sweden (P<.001). In the cross-sectional survey, the mean (SD) estimated percentage of patients missing a treatment per month was 4% (3%) for the United States, 0% for Japan, and 0.1% (3%) for Sweden (P<.001).Conclusions  Noncompliance is much more common in US patients undergoing hemodialysis than Swedish and Japanese patients. The implications of these results for international differences in survival deserve further study. SN - 0098-7484 M3 - doi: 10.1001/jama.281.13.1211 UR - http://dx.doi.org/10.1001/jama.281.13.1211 ER -