TY  - JOUR
T1  - WEll-being of patients with dementia and their caregivers after a biobehavioral home-based intervention
AU  - Gitlin LN, Hauck WW, Winter L
Y1  - 2010/12/08
N1  - 10.1001/jama.2010.1790
JO  - JAMA
SP  - 2482
EP  - 2484
VL  - 304
IS  - 22
N2  - 
Because our only data before 4 months (the primary end point) were from baseline, our choices for managing missing data from dropouts were limited. We rejected last observation carried forward because of its biasing effect when both groups naturally change from baseline to follow-up. We did deviate from ITT in that families who missed follow-up assessments were not included. However, we retained the ITT principle; all study participants with follow-up data were included in analyses regardless of participation level. This approach is used in other large-scale multisite nonpharmacologic interventions with caregivers and dementia patients.1- 2

SN  - 0098-7484
M3  - doi: 10.1001/jama.2010.1790
UR  - http://dx.doi.org/10.1001/jama.2010.1790
ER  -