TY  - JOUR
T1  - BArring the door to hsv-1
AU  - Friedrich MJ
Y1  - 2010/11/17
N1  - 10.1001/jama.2010.1669
JO  - JAMA
SP  - 2116
EP  - 2116
VL  - 304
IS  - 19
N2  - 
Although earlier work revealed that HSV-1 interacts with cellular receptors for the glycoproteins B and D that reside on the viral surface to gain entry into a host cell, not all entry receptors have been identified. In the new work, the investigators used a proteomics-based search for molecules interacting with HSV-1 and found that the protein non–muscle myosin heavy chain IIA (NMHC-IIA), a subunit of non–muscle myosin IIA, serves as a functional entry receptor that interacts with glycoprotein B.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2010.1669
UR  - http://dx.doi.org/10.1001/jama.2010.1669
ER  -