TY  - JOUR
T1  - SCreening colonoscopy vs flexible sigmoidoscopy—reply
AU  - Neugut AI, Lebwohl B
Y1  - 2010/11/10
N1  - 10.1001/jama.2010.1586
JO  - JAMA
SP  - 2016
EP  - 2018
VL  - 304
IS  - 18
N2  - 
As both letters affirm, the reasons for the lack of effect of colonoscopy in the proximal colon may reflect correctable problems, such as the specialty and skill of the colonoscopist or other variations in performance. Nonetheless, these data reflect how colonoscopy is currently performed on a population scale, at least in Canada and Germany. Whether colonoscopy by a cadre of extremely expert colonoscopists would yield improved right-sided mortality is only speculative. But what matters is what happens in the real world (the distinction between effectiveness and idealized efficacy).

SN  - 0098-7484
M3  - doi: 10.1001/jama.2010.1586
UR  - http://dx.doi.org/10.1001/jama.2010.1586
ER  -