TY - JOUR T1 - EFfects of low-dose growth hormone withdrawal in patients with hiv AU - Lo J, You S, Liebau J, Lee H, Grinspoon S Y1 - 2010/07/21 N1 - 10.1001/jama.2010.989 JO - JAMA SP - 272 EP - 274 VL - 304 IS - 3 N2 - To the Editor: In an 18-month randomized placebo-controlled study of patients with human immunodeficiency virus (HIV) having abdominal fat accumulation and relative growth hormone (GH) deficiency, low-dose, long-term GH reduced visceral adipose tissue (VAT) but worsened glucose control.1 To investigate changes in VAT and other parameters after GH discontinuation, data from an extension in which participants crossed over from their initial treatment (months 0-18) to the opposite treatment (immediately after the month 18 visit through month 36) were analyzed. SN - 0098-7484 M3 - doi: 10.1001/jama.2010.989 UR - http://dx.doi.org/10.1001/jama.2010.989 ER -