TY  - JOUR
T1  - MEdication helps make therapy work for teens addicted to prescription opioids
AU  - Kuehn BM
Y1  - 2010/06/16
N1  - 10.1001/jama.2010.789
JO  - JAMA
SP  - 2343
EP  - 2345
VL  - 303
IS  - 23
N2  - 
Yet medications, such as buprenorphine, can greatly improve patients' adherence to treatment. Garrett, who acknowledged that he was initially skeptical of using prescription drugs to treat patients with these addictions, explained that talk and behavioral therapies can do little to ease the symptoms of withdrawal and strong drug craving that often lead patients to relapse to drug use. But buprenorphine, a partial opioid agonist often paired with naloxone to reduce abuse potential, has been demonstrated in a randomized controlled trial to increase patient retention and improve outcomes (Woody GE et al. JAMA. 2008;300[17]:2003-2011). Now scientists are working to build on this and other emerging evidence to develop therapies targeted to the unique needs of this patient population.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2010.789
UR  - http://dx.doi.org/10.1001/jama.2010.789
ER  -