TY - JOUR T1 - IMproving medication adherence promises great payback, but poses tough challenge AU - Mitka M Y1 - 2010/03/03 N1 - 10.1001/jama.2010.212 JO - JAMA SP - 825 EP - 825 VL - 303 IS - 9 N2 - Poor adherence accounts for an estimated 33% to 69% of medication-related hospital admissions, costing about $100 billion (Osterberg L and Blaschke L. N Engl J Med. 2005;353[5]:487-497). Harder to measure, but no less real, are the premature deaths and reduced quality of life for patients; increased patient and physician anger, frustration, and hopelessness; and skewed findings for clinical research. SN - 0098-7484 M3 - doi: 10.1001/jama.2010.212 UR - http://dx.doi.org/10.1001/jama.2010.212 ER -