TY  - JOUR
T1  - COcaine addiction
AU  - Kuehn BM
Y1  - 2010/02/24
N1  - 10.1001/jama.2010.166
JO  - JAMA
SP  - 722
EP  - 722
VL  - 303
IS  - 8
N2  - 
Previous studies have demonstrated that repeated cocaine administration leads to persistent changes both in gene expression and in the structure of the nucleus accumbens of the brain. Now a multi-institutional team of scientists has demonstrated, through a series of experiments in mice, that repeated cocaine administration suppresses the activity of G9A, an enzyme that helps regulate whether genes are turned on or off (Maze I et al. Science. 2010;327[5962]:213-216).

SN  - 0098-7484
M3  - doi: 10.1001/jama.2010.166
UR  - http://dx.doi.org/10.1001/jama.2010.166
ER  -