TY - JOUR T1 - NEw findings challenge thinking about anemia, iron deficiency, and heart risk AU - Mitka M Y1 - 2010/02/03 N1 - 10.1001/jama.2010.37 JO - JAMA SP - 405 EP - 406 VL - 303 IS - 5 N2 - Anemia serves as a biomarker because lower hemoglobin levels are associated with higher rates of cardiovascular and renal events. One treatment strategy is to use erythropoiesis-stimulating agents (ESAs) to increase hemoglobin levels. ESAs have been found to reduce the need for red-cell transfusions and improve such patient quality-of-life factors as fatigue. But until lately, ESAs had not been tested against a placebo, so their effects on hard clinical end points such as reducing the risk of a cardiovascular event or death had remained unknown. SN - 0098-7484 M3 - doi: 10.1001/jama.2010.37 UR - http://dx.doi.org/10.1001/jama.2010.37 ER -