TY - JOUR T1 - EPigenetic therapies offer new approach to fighting cancer at the genetic level AU - Friedrich MJ Y1 - 2010/01/20 N1 - 10.1001/jama.2009.1914 JO - JAMA SP - 213 EP - 214 VL - 303 IS - 3 N2 - Three drugs that target epigenetic pathways are now used in the clinic to treat hematologic malignancies, and many more agents are in the pipeline. Oncologists are taking lessons learned at the bedside back to the bench to better understand how these therapies work and how resistance to them develops, said Jean-Pierre Issa, MD, professor of medicine at the University of Texas M. D. Anderson Cancer Center in Houston. SN - 0098-7484 M3 - doi: 10.1001/jama.2009.1914 UR - http://dx.doi.org/10.1001/jama.2009.1914 ER -