TY  - JOUR
T1  - CLue to arthritis spread
AU  - Stephenson J
Y1  - 2009/12/16
N1  - 10.1001/jama.2009.1839
JO  - JAMA
SP  - 2531
EP  - 2531
VL  - 302
IS  - 23
N2  - 
The researchers implanted healthy human cartilage with RASFs from patients with rheumatoid arthritis under the skin of immunodeficient mice; cartilage without fibroblasts was implanted on the opposite flank. The synovial fibroblasts attacked not only the cartilage with which they were coimplanted, they also actively migrated through blood vessels to the other side, leading to cartilage destruction in the previously RASF-free site as well.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2009.1839
UR  - http://dx.doi.org/10.1001/jama.2009.1839
ER  -