TY - JOUR T1 - INtraoperative diagnosis and management of patent foramen ovale AU - Mirakaj V, Thix CA, Rosenberger P Y1 - 2009/12/02 N1 - 10.1001/jama.2009.1743 JO - JAMA SP - 2317 EP - 2318 VL - 302 IS - 21 N2 - To the Editor: Dr Krasuski and colleagues1 investigated the association of intraoperative patent foramen ovale (PFO) closure with perioperative outcomes and long-term survival. The study found that the risk of perioperative stroke was not associated with closure of a PFO at the time of incidental intraoperative discovery. Technical advancement and the widespread use of intraoperative transesophageal echocardiography (TEE) have increased the incidence of diagnosing a PFO at the time of surgery and have raised questions about best possible management.2- 3 SN - 0098-7484 M3 - doi: 10.1001/jama.2009.1743 UR - http://dx.doi.org/10.1001/jama.2009.1743 ER -