TY  - JOUR
T1  - BIomarkers for prediction of cardiovascular events
AU  - Cook NR
Y1  - 2009/11/18
N1  - 10.1001/jama.2009.1636
JO  - JAMA
SP  - 2089
EP  - 2090
VL  - 302
IS  - 19
N2  - 
To the Editor: Dr Melander and colleagues1 suggested that gains in risk prediction using new biomarkers for cardiovascular disease are minimal using risk reclassification, a technique that can help determine whether new markers can change clinical decisions.2 In contrast to similar analyses using data from the Women's Health Study, the Physicians' Health Study, and the Framingham Heart Study, there was no improvement in risk stratification with new markers, including C-reactive protein (CRP).

SN  - 0098-7484
M3  - doi: 10.1001/jama.2009.1636
UR  - http://dx.doi.org/10.1001/jama.2009.1636
ER  -