TY  - JOUR
T1  - POlymyxin b hemoperfusion and mortality in abdominal septic shock
AU  - Kida Y
Y1  - 2009/11/11
N1  - 10.1001/jama.2009.1608
JO  - JAMA
SP  - 1968
EP  - 1970
VL  - 302
IS  - 18
N2  - 
To the Editor:  Dr Cruz and colleagues1 concluded that polymyxin B hemoperfusion added to conventional therapy reduced 28-day mortality in patients with severe sepsis or septic shock from intra-abdominal gram-negative infections. However, Table 2 in their article showed that gram-positive bacteria such as Enterococcus, Staphylococcus, and Streptococcus were more frequently isolated in the polymyxin B hemoperfusion group than the conventional therapy group. Therefore, the frequencies of gram-negative sepsis and severe endotoxemia seemed to be high in the conventional therapy group compared with the polymyxin B hemoperfusion group.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2009.1608
UR  - http://dx.doi.org/10.1001/jama.2009.1608
ER  -