TY  - JOUR
T1  - DEpression in at-risk adolescents and their parents
AU  - Weissman MM, Talati A
Y1  - 2009/09/16
N1  - 10.1001/jama.2009.1329
JO  - JAMA
SP  - 1167
EP  - 1168
VL  - 302
IS  - 11
N2  - 
An ancillary study of children of parents receiving treatment as part of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) found that remission of maternal depression after 3 months of medication was significantly associated with reductions in the children's diagnoses and symptoms.2 Conversely, a failure to remit was associated with worsening in child outcomes, paralleling observations by Garber et al that cognitive behavioral therapy did not confer a protective effect among the offspring of currently depressed parents. The STAR*D findings were sustained in offspring of mothers who remitted later after the first 3 months of treatment3 and were supported by consistent findings in an independent randomized controlled trial covering 9 months and using another evidence-based psychotherapy for the depressed mothers.4

SN  - 0098-7484
M3  - doi: 10.1001/jama.2009.1329
UR  - http://dx.doi.org/10.1001/jama.2009.1329
ER  -