TY  - JOUR
T1  - Dr william w. duke: Pioneer in platelet research
AU  - Kickler T
Y1  - 2009/06/03
N1  - 10.1001/jama.2009.787
JO  - JAMA
SP  - 2267
EP  - 2269
VL  - 301
IS  - 21
N2  - 
In 1910, when Duke1 published an article in JAMA on the role of platelets in hemostasis, probably few individuals realized that this report would be judged as one of the outstanding contributions to the science of medicine during the first half of the 20th century.2 The application of a simple, low-tech approach to answering the elusive role of platelets in hemostasis provided the foundation for many subsequent developments in platelet biology and therapy. This Commentary will focus on Duke's observations and on how his observations have led to improved understanding of the pathophysiology, diagnosis, and treatment of platelet-related disorders.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2009.787
UR  - http://dx.doi.org/10.1001/jama.2009.787
ER  -