TY - JOUR T1 - REspiratory rate and diagnosis of pleural effusion—reply AU - Wong CL, Holroyd-Leduc JM, Straus SE Y1 - 2009/05/20 N1 - 10.1001/jama.2009.654 JO - JAMA SP - 1989 EP - 1990 VL - 301 IS - 19 N2 - In Reply: We concur with Dr Manning that the respiratory rate is an important component of the physical examination; it may identify patients who require more intensive monitoring or further investigation. Our search strategy in this systematic review included search terms such as vital sign, clinical observation, and mouth breathing, and also a hand-search of the bibliographies of retrieved articles. Surprisingly, we did not identify any studies meeting our inclusion and exclusion criteria that discussed the diagnostic accuracy of respiratory rate in the context of pleural effusion. This certainly would be an interesting study for patients presenting with pulmonary symptoms suspected of pleural effusion. SN - 0098-7484 M3 - doi: 10.1001/jama.2009.654 UR - http://dx.doi.org/10.1001/jama.2009.654 ER -