TY - JOUR T1 - EQuivalence of generic and brand-name drugs for cardiovascular disease AU - Reiffel JA Y1 - 2009/04/22 N1 - 10.1001/jama.2009.522 JO - JAMA SP - 1654 EP - 1656 VL - 301 IS - 16 N2 - To the Editor: Although the observations of Dr Kesselheim and colleagues1 are generally accurate, the authors oversimplified the issue and did not adequately consider all of the evidence. They largely grouped the material they reviewed into clinical trials and editorials. The former were appropriately given more weight in the authors' conclusions. However, case report material in some editorials as well as in articles that were not included2 (such as reports of serious arrhythmic recurrences, proarrhythmic events, and deaths in association with formulation substitution of an antiarrhythmic drug) was ignored. SN - 0098-7484 M3 - doi: 10.1001/jama.2009.522 UR - http://dx.doi.org/10.1001/jama.2009.522 ER -