TY  - JOUR
T1  - ABuse and the brain
AU  - Stephenson J
Y1  - 2009/04/01
N1  - 10.1001/jama.2009.428
JO  - JAMA
SP  - 1329
EP  - 1329
VL  - 301
IS  - 13
N2  - 
The investigators examined brain tissue from 24 men who had committed suicide, half of whom had a history of childhood abuse, and from 12 men who had not been abused and died suddenly from other causes. Men with a history of abuse had lower levels of glucocorticoid receptors than did men who had not been abused or had not committed suicide. In addition, in those who had been abused, a snippet of “promoter” DNA that normally facilitates the production of glucocorticoid receptors had been silenced by the attachment of a methyl group.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2009.428
UR  - http://dx.doi.org/10.1001/jama.2009.428
ER  -