TY - JOUR T1 - SIlicone breast implants and anaplastic large t-cell lymphoma AU - van der Veldt AM, Kleijn SA, Nanayakkara PW Y1 - 2009/03/25 N1 - 10.1001/jama.2009.279 JO - JAMA SP - 1227 EP - 1227 VL - 301 IS - 12 N2 - To the Editor: In a case-control study, Dr de Jong and colleagues1 reported a possible association between silicone breast implants and anaplastic large T-cell lymphoma (ALCL). Although histological material of breast lymphomas was retrieved and additional immunohistochemistry and molecular studies were performed, the authors did not report on the presence of foreign bodies and foreign body reactions adjacent to the breast lymphomas. Apart from leakage and rupture, silicone gel can migrate through the intact silicone elastomer shell, a process that is called bleeding.2 SN - 0098-7484 M3 - doi: 10.1001/jama.2009.279 UR - http://dx.doi.org/10.1001/jama.2009.279 ER -