TY  - JOUR
T1  - CAncer drug target?
AU  - Friedrich MJ
Y1  - 2009/02/04
N1  - 10.1001/jama.2009.41
JO  - JAMA
SP  - 477
EP  - 477
VL  - 301
IS  - 5
N2  - 
In studies in zebrafish embryos, the researchers identified a DNA demethylation process that involves the coupling of these 2 enzymes and a nonenzymatic factor. Defects in DNA methylation, a cellular process that shuts off genes that either aren't needed or are malfunctioning, can lead to the development of cancer and other diseases.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2009.41
UR  - http://dx.doi.org/10.1001/jama.2009.41
ER  -