TY  - JOUR
T1  - PRotective ventilation for patients without acute respiratory distress syndrome—reply
AU  - Serpa Neto A, Schultz MJ
Y1  - 2013/02/20
N1  - 10.1001/jama.2012.197021
JO  - JAMA
SP  - 654
EP  - 654
VL  - 309
IS  - 7
N2  - 
Dr Fuller and colleagues question our search strategy and suggest that some eligible studies were not included.1- 2 A number of studies were excluded because they described only odds ratios and not absolute numbers, which we used in the data calculation, and also because they stratified the groups by ARDS vs non-ARDS and not by low vs high tidal volume. In the study by Gajic et al,3 36 patients were not included in the meta-analysis because they were in an intermediate tidal volume group. Regarding the study by Fernandez-Bustamante et al,4 we included the patients with oxygenation criteria for ARDS. We ran another analysis without this study, which did not report radiographic criteria, and found similar results (RR, 0.31 [95% CI, 0.21-0.45]).

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.197021
UR  - http://dx.doi.org/10.1001/jama.2012.197021
ER  -