TY - JOUR T1 - PRotective ventilation for patients without acute respiratory distress syndrome AU - Fuller BM, Mohr NM, Carpenter CR Y1 - 2013/02/20 N1 - 10.1001/jama.2012.197018 JO - JAMA SP - 654 EP - 654 VL - 309 IS - 7 N2 - First, given the inclusion criteria, it is unclear how the authors excluded several important studies2- 3 examining the role of tidal volume in the development of ARDS. In the study by Gajic et al4 that was included in the review, 80 patients developed lung injury, yet the authors included an assessment of only 44 patients in their meta-analysis. What happened to the other 36 patients who developed lung injury? Regarding the study by Fernandez-Bustamante et al,5 Serpa Neto et al claimed that 12 patients progressed to lung injury despite the fact that the original article stated that “no radiographic criteria were available to assess acute lung injury.” SN - 0098-7484 M3 - doi: 10.1001/jama.2012.197018 UR - http://dx.doi.org/10.1001/jama.2012.197018 ER -