TY - JOUR T1 - HIgh-cholesterol pigs AU - Hampton T Y1 - 2013/02/06 N1 - 10.1001/jama.2013.54 JO - JAMA SP - 431 EP - 431 VL - 309 IS - 5 N2 - The researchers inserted a mutated form of the gene that encodes proprotein convertase subtilisin kexin type 9 (PCSK9) into Yucatan minipigs. Humans with mutated PCSK9 develop severe hypercholesterolemia and early atherosclerotic vascular disease. SN - 0098-7484 M3 - doi: 10.1001/jama.2013.54 UR - http://dx.doi.org/10.1001/jama.2013.54 ER -