TY  - JOUR
T1  - Prespecified falsification end points: Can they validate true observational associations?
AU  - Prasad V, Jena AB
Y1  - 2013/01/16
N1  - 10.1001/jama.2012.96867
JO  - JAMA
SP  - 241
EP  - 242
VL  - 309
IS  - 3
N2  - 
As observational studies have increased in number—fueled by a boom in electronic recordkeeping and the ease with which observational analyses of large databases can be performed—so too have failures to confirm initial research findings.1 Several solutions to the problem of incorrect observational results have been suggested,1- 2 emphasizing the importance of a record not only of significant findings but of all analyses conducted.2

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.96867
UR  - http://dx.doi.org/10.1001/jama.2012.96867
ER  -