TY  - JOUR
T1  - SPect/ct for sentinel lymph node detection in patients with melanoma
AU  - Dupuy A, Heusse J
Y1  - 2013/01/16
N1  - 10.1001/jama.2012.88570
JO  - JAMA
SP  - 232
EP  - 233
VL  - 309
IS  - 3
N2  - 
To the Editor: Dr Stoffels and colleagues1 evaluated disease-free survival in a series of consecutive patients with melanoma seen in a single center who underwent sentinel lymph node (SLN) excision after preoperative single-photon emission computed tomography/computed tomography (SPECT/CT) detection. A comparison was made to historical controls from the same center who had SLN detection without preoperative SPECT/CT. The SPECT/CT cohort presented with significantly more SLNs detected per patient and a higher number of positive SLNs per patient. Being in the standard cohort rather than in the SPECT/CT cohort was strongly associated with worse disease-free survival (hazard ratio, 4.11; 95% CI, 1.25-13.51) in a multivariate Cox model including SLN status and other important prognostic factors.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.88570
UR  - http://dx.doi.org/10.1001/jama.2012.88570
ER  -