TY - JOUR T1 - STrategies for tailoring asthma treatment in adults—reply AU - Calhoun WJ, Boushey HA, Ameredes BT, Asthma Clinical Research Network BASALT Trial Investigators f Y1 - 2013/01/09 N1 - 10.1001/jama.2012.73385 JO - JAMA SP - 136 EP - 137 VL - 309 IS - 2 N2 - Although the performance characteristics of sputum eosinophils is slightly better than that of exhaled nitric oxide, the penetrance of sputum eosinophil measurements into clinical practice in the United States and in most of the world has been negligible due to the difficulty of establishing reproducible and reliable sputum processing and cytological examination in the clinical setting. Someday sputum measures may be made reproducibly and technically simple enough to be performed routinely in the office setting, but the state of standard clinical technology is not there yet. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.73385 UR - http://dx.doi.org/10.1001/jama.2012.73385 ER -