TY  - JOUR
T1  - STrategies for tailoring asthma treatment in adults
AU  - Sterk PJ, Sont JK
Y1  - 2013/01/09
N1  - 10.1001/jama.2012.73379
JO  - JAMA
SP  - 135
EP  - 136
VL  - 309
IS  - 2
N2  - 
The BASALT trial is an example of an asthma treatment algorithm study.2 These kind of studies aim to improve clinical outcome by tailoring treatment with existing drugs based on predefined levels of a quantitative disease marker. The design of such trials is pivotal, including choices regarding the patient population, definition of the clinical end point, clinical room for improvement, selection of the disease marker, discrete levels of the marker leading to treatment changes, and dose adjustments of the drug.3

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.73379
UR  - http://dx.doi.org/10.1001/jama.2012.73379
ER  -