TY - JOUR T1 - EXperimental malaria vaccine AU - Friedrich MJ Y1 - 2012/12/19 N1 - 10.1001/jama.2012.128613 JO - JAMA SP - 2449 EP - 2449 VL - 308 IS - 23 N2 - In the phase 3 trial, 6537 infants who were between 6 and 12 months old at the time of the first vaccination received 3 doses of either the RTS,S/AS01 candidate vaccine or a nonmalaria comparator vaccine at 1-month intervals along with standard childhood vaccines. An analysis of the incidence of malaria in infants for 12 months after the third vaccine dose found that the RTS,S/AS01 vaccine reduced the risk of detectable malaria and severe malaria by 31% and 37%, respectively, compared with controls. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.128613 UR - http://dx.doi.org/10.1001/jama.2012.128613 ER -