TY  - JOUR
T1  - HElp for ex-smokers?
AU  - Hampton T
Y1  - 2012/12/12
N1  - 10.1001/jama.2012.111754
JO  - JAMA
SP  - 2326
EP  - 2326
VL  - 308
IS  - 22
N2  - 
A new inhibitor can help previously nicotine-addicted rats avoid relapse. Researchers from the University of Toronto found that long-term nicotine exposure causes 2 ligand-gated ion channels—α7 nicotinic acetylcholine receptors (α7nAChRs) and NMDA glutamate receptors (NMDARs)—to interact and form a protein complex in the brain and that this interaction can be disrupted by an inhibitor (Li S et al. J Exp Med. doi: 10.1084/jem.20121270 [published online October 22, 2012]).

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.111754
UR  - http://dx.doi.org/10.1001/jama.2012.111754
ER  -