TY  - JOUR
T1  - SCientists confront joint hiv-tb epidemics by taking fight to the front lines
AU  - Kuehn BM
Y1  - 2012/11/21
N1  - 10.1001/jama.2012.14752
JO  - JAMA
SP  - 1959
EP  - 1960
VL  - 308
IS  - 19
N2  - 
The emergence of extensively drug-resistant tuberculosis (XDR-TB) in patients at a rural hospital in the KwaZulu-Natal province of South Africa gained international attention in 2005. By that point, physicians had become accustomed to encountering cases of multidrug-resistant TB (MDR-TB). When first-line antibiotics failed, they knew they could turn to more toxic and less effective second-line choices. But the outbreak in KwaZulu-Natal led to the “recognition that untreatable TB was out there,” explained William R. Bishai, MD, PhD, codirector of the Johns Hopkins Center for Tuberculosis Research in Baltimore.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.14752
UR  - http://dx.doi.org/10.1001/jama.2012.14752
ER  -