TY - JOUR T1 - PRevention of fatal opioid overdose AU - Beletsky L, Rich JD, Walley AY Y1 - 2012/11/14 N1 - 10.1001/jama.2012.14205 JO - JAMA SP - 1863 EP - 1864 VL - 308 IS - 18 N2 - During the time it typically takes some overdoses to turn fatal, it is possible to reverse the respiratory depression and other effects of opioids with the antagonist naloxone. Community-based organizations, health care institutions, and local and state agencies have begun to train and equip potential nonmedical bystanders to recognize and reverse overdose events using first aid techniques and emergency supplies of naloxone.2- 3 As the number of such initiatives has increased, the 53 000 program trainees have tracked more than 10 000 reports of overdose rescues in the United States.2 These efforts have targeted drug users (syringe access programs, drug treatment centers, correctional facilities),1 physicians (to “co-prescribe” naloxone along with opioids),4 and first responders (ie, fire and police).3 The concept has also gained traction among policy makers, including the Office of the National Drug Control Policy and professional organizations.5 SN - 0098-7484 M3 - doi: 10.1001/jama.2012.14205 UR - http://dx.doi.org/10.1001/jama.2012.14205 ER -