TY - JOUR T1 - PRotective gene for malaria? AU - Friedrich MJ Y1 - 2012/10/17 N1 - 10.1001/jama.2012.13775 JO - JAMA SP - 1515 EP - 1515 VL - 308 IS - 15 N2 - The investigators performed genetic tests for the SAO defect in 1975 children from the Madang area of Papua New Guinea who were enrolled in 3 separate malaria studies: a clinical drug prevention trial with 1121 infants aged 3 to 21 months, a case-control study of 318 children with severe malaria aged 10 years and younger, and a treatment time-to-reinfection study of 206 children aged 5 to 14 years. In the 3 studies, the SAO genetic defect was associated with a reduction in risk of clinical P vivax episodes. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.13775 UR - http://dx.doi.org/10.1001/jama.2012.13775 ER -