TY - JOUR T1 - THe problem with peripherally inserted central catheters AU - Chopra V, Flanders SA, Saint S Y1 - 2012/10/17 N1 - 10.1001/jama.2012.12704 JO - JAMA SP - 1527 EP - 1528 VL - 308 IS - 15 N2 - Consequently, studies to predict and prevent these complications have become a research priority. Because of the frequent use of CVCs in the intensive care unit (ICU), efforts to reduce these unfavorable outcomes have traditionally focused on critically ill patients, a population for which substantial progress has been made. For example, improvements in measurement of infectious episodes by standardized definitions and diffusion of evidence-based practices have led to a 58% decrease in CLABSI in ICUs across the United States.1 Similarly, evidence-based guidelines emphasizing risk estimation and pharmacological prophylaxis have decreased the risk of CVC-related venous thromboembolism in ICU patients. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.12704 UR - http://dx.doi.org/10.1001/jama.2012.12704 ER -