TY  - JOUR
T1  - BLeeding disorders
AU  - Goodman DM, Burke AE, Livingston EH
Y1  - 2012/10/10
N1  - 10.1001/jama.2012.4089
JO  - JAMA
SP  - 1492
EP  - 1492
VL  - 308
IS  - 14
N2  - 
When tissues are injured, blood cell fragments called platelets  gather at the wound, providing a foundation for coagulation  (clotting). Platelets are bound together by a glue-like protein named von Willebrand factor. Once the initial platelet plug is built, clotting factors gather at the injury site to seal the wound, stop bleeding, and begin the healing process. The clotting factors work in a carefully timed sequence, resulting in a sturdy clot and healed wound.

SN  - 0098-7484
M3  - doi: 10.1001/jama.2012.4089
UR  - http://dx.doi.org/10.1001/jama.2012.4089
ER  -