TY - JOUR T1 - OFf-label use of bone morphogenetic proteins in pediatric spinal arthrodesis AU - Dodwell E, Snyder B, Wright J Y1 - 2012/10/10 N1 - 10.1001/jama.2012.12929 JO - JAMA SP - 1429 EP - 1432 VL - 308 IS - 14 N2 - Bone morphogenetic proteins (BMPs) are approved for limited use in adults when healing may be suboptimal.2- 3 In addition to concerns about possible carcinogenesis, complications include wound dehiscence, spinal stenosis, and respiratory complications.4 The US Food and Drug Administration has not approved the use of BMPs in children. SN - 0098-7484 M3 - doi: 10.1001/jama.2012.12929 UR - http://dx.doi.org/10.1001/jama.2012.12929 ER -