TY  - JOUR
T1  - TReatment of sepsis-related organ dysfunction—reply
AU  - Welte T, Brunkhorst F, Kuhnt E
Y1  - 2012/09/26
N1  - 10.1001/2012.jama.11271
JO  - JAMA
SP  - 1206
EP  - 1207
VL  - 308
IS  - 12
N2  - 
In Reply:  Both Dr Rodríguez-Baño and Dr Du and colleagues raise similar concerns that the treatment options of meropenem monotherapy vs meropenem plus moxifloxacin used in our study appear to contradict current guidelines for the treatment of severe community-acquired pneumonia, which recommend a combination of a β-lactam and a macrolide or an antipseudomonal β-lactam combined with an aminoglycoside or ciprofloxacin in cases of suspected Pseudomonas infection.1 While we agree with these recommendations for treating pneumonia, our study focused on patients with severe sepsis and septic shock independent of the focus of infection.

SN  - 0098-7484
M3  - doi: 10.1001/2012.jama.11271
UR  - http://dx.doi.org/10.1001/2012.jama.11271
ER  -