TY - JOUR T1 - STudies probe mechanisms that have a role in obesity-associated morbidities AU - Friedrich MJ Y1 - 2012/09/19 N1 - 10.1001/2012.jama.11024 JO - JAMA SP - 1077 EP - 1079 VL - 308 IS - 11 N2 - Although researchers have yet to discover a unifying pathological mechanism underlying the development of metabolic syndrome, they have learned much about how excess adiposity can perturb normal metabolic functions. In particular, the relationship between obesity and chronic low-grade inflammation in various tissues of the body, such as adipose tissue, has been the subject of intense research. SN - 0098-7484 M3 - doi: 10.1001/2012.jama.11024 UR - http://dx.doi.org/10.1001/2012.jama.11024 ER -